Steroids have been found to possess a unique ability to reduce heart damage in children with Kawasaki’s disease, according to a study that was published in an issue of Pediatrics.
It is important to note here that the findings of this study highlight knowledge gap as the present guidelines from the American Academy of Pediatrics state that there is little evidence to suggest that steroids are effective in treating children with Kawasaki’s disease when it comes to minimizing damage to heart. The study also suggested that recommendations are been made for the standard treatment of Kawasaki’s via aspirin and intravenous immunoglobulin (IVIG).
“This gap in knowledge led us to examine the benefits of steroids more closely. We looked at research worldwide and were surprised to find eight solid clinical trials showing the value of steroids in significantly reducing heart damage in children with Kawasaki’s disease. Steroids, when combined with aspirin and IVGB, reduced the odds of developing inflammation of the heart blood vessels by half,” said Stephen Aronoff, MD, lead author of the meta-analysis and Temple University School of Medicine professor and chair of pediatrics.
It was remarked by Aronoff, MD, lead author of the meta-analysis and Temple University School of Medicine professor and chair of pediatrics that a multi-center study will be able to offer any further proofs for justifying the benefits of steroid treatment for Kawasaki’s disease, which is considered to be one of the leading causes of acquired heart disease in children inflaming the blood vessels leading to the heart.
Popularity: 6% [?]